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Author Topic: understanding molecular issues  (Read 1302 times)
rich
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« on: February 16, 2003, 04:34:29 AM »

I have just finished reading a 30 page debate from another board re Eswarans paper.
While I am aware of the basics re DNA 'tracking', then comes the issues of haplotypes, linkage disequilibrium, pairwaise distance distribution, allotypes, etc etc,.
Can anyone give an insight or a few references to ease my confusion. I appreciate some have spent years in attaining the knowledge they have now, and I imagine there is no easy fix, but its just a 'genetics for dummies' thing I want to begin with. I think it would help others too.
Reagrds,
Rich
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richard
John Goodrum
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« Reply #1 on: February 16, 2003, 01:15:01 PM »


Can anyone give an insight or a few references to ease my confusion. I appreciate some have spent years in attaining the knowledge they have now, and I imagine there is no easy fix, but its just a 'genetics for dummies' thing I want to begin with. I think it would help others too.



Quite a bit of good introductory material has been put on the web for students taking college courses in genetics.  I've taken advantage of this and haven't felt guilty about it.  One of the best sites I've seen is here:

http://bioweb.wku.edu/courses/Biol430/430summaries.htm


John
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Daryl Habel
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« Reply #2 on: February 16, 2003, 05:11:42 PM »

C. David Kreger has, as part of his webpage, an excellent dictionary of definitions, very helpful with jargon of both molecular and physical studies.

http://www.modernhumanorigins.com/definitions.html

Dar
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Daryl Habel
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Dale Hoogeveen
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« Reply #3 on: February 16, 2003, 08:53:06 PM »

Hi Rich,

For meiosis:

Dr. James C. Major, Jr.  On line lecture:
http://www.esb.utexas.edu/major/zoo321h/lectures/lecture2.html
SPERMATIOGENESIS and OÖGENESIS sections
and a very basic but quite complete overview of meiosis:
http://www.biology.iupui.edu/biocourses/N100H/ch9meiosis.html

For mitochondria:

Mervi Lehtonen, Department of Neurology, University of Oulu
(includes a a survey of mtDNA literature in Chapter 2.)
http://herkules.oulu.fi/isbn9514268490/html/c347.html

or the total composition available as a 98 page PDF at
http://herkules.oulu.fi/isbn9514268490/
(http://herkules.oulu.fi/isbn9514268490/isbn9514268490.pdf)

Also here.

Dutch


I have just finished reading a 30 page debate from another board re Eswarans paper.
While I am aware of the basics re DNA 'tracking', then comes the issues of haplotypes, linkage disequilibrium, pairwaise distance distribution, allotypes, etc etc,.
Can anyone give an insight or a few references to ease my confusion. I appreciate some have spent years in attaining the knowledge they have now, and I imagine there is no easy fix, but its just a 'genetics for dummies' thing I want to begin with. I think it would help others too.
Reagrds,
Rich
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Peace
Dale Hoogeveen
rich
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« Reply #4 on: February 20, 2003, 07:19:39 AM »

thanks to Dutch, Dar and John for those references. I will read through them in the next few weeks.
Regards,
Rich
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richard
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